Comparación de sutura mecánica con sutura manual de la faringe en laringectomía total / Comparison of mechanical suture with manual suture of the pharynx in total laryngectomy

Introducción: La sutura mecánica es una opción para el cierre de la faringorrafia en laringectomía total por cáncer de laringe. Objetivo: Comparar el uso de sutura mecánica lineal con sutura manual de la faringe durante la laringectomía total por cáncer de laringe. Material y Método: Se realizó un estudio de tipo experimental prospectivo. Se compararon dos grupos pacientes: Los pacientes con sutura mecánica desde 2018 a marzo de 2020 y los pacientes con sutura manual previa a enero de 2018 en el Servicio de Otorrinolaringología del Hospital Barros Luco. Se analizaron fístula faringo-cutánea posoperatoria (FFC), tiempo operatorio, estadía hospitalaria y costo. Resultados: El estudio incluyó a 14 pacientes, cada grupo con n = 7. El grupo con sutura mecánica presento 0% de FFC y el grupo sutura manual 28%. El grupo con sutura mecánica reinicio alimentación a los 7 días y el grupo con sutura manual en promedio a los 11,5 (7-23) días. (p = 0,0023). El tiempo promedio de cirugía para el grupo experimental es de 288 ± 37,4 minutos y con sutura manual 311 ± 32,4 minutos. (p = 0,0176). El promedio de hospitalización para el grupo experimental fue de 11 ± 2,6 días (9 a 16), y para el grupo control fue de 21 ± 14 días (10 a 49) (p < 0,0001). Conclusión: La sutura mecánica es un procedimiento fácil de usar y seguro. Existiría un beneficio en el uso de sutura mecánica para el cierre faríngeo al compararlo con la sutura manual al disminuir el número de FFC, el tiempo operatorio y los días de hospitalización.

Introduction: Mechanical suture is an option for the closure of the pharyngorrhaphy in total laryngectomy due to laryngeal cancer. Aim: To compare the use of linear mechanical suture with manual pharyngeal suture during total laryngectomy for laryngeal cancer. Material and Method: A prospective experimental study was carried out. Two patient groups were compared: patients with mechanical suture from 2018 to March 2020 and patients with manual suture prior to January 2018 at the otorhinolaryngology service of the Barros Luco Hospital. Postoperative pharyngocutaneous fistula (FFC), operative time, hospital stay and cost were analyzed. Results: The study included 14 patients, each group with n = 7. The group with mechanical suture presented 0% of FFC and the group with manual suture 28%. The group with mechanical suture restarted feeding at 7 days and the group with manual suture on average at 11.5 (7-23) days (p = 0.0023). The average surgery time for the experimental group was 288 ± 37.4 minutes, while for the group with manual suture was 311 ± 32.4 minutes (p = 0.0176). The mean hospitalization for the experimental group was 11 ± 2.6 days (9 to 16), and for the control group it was 21 ± 14 days (10 to 49) (p < 0.0001). Conclusion: The mechanical suture is an easy to use and safe procedure. There would be a benefit in the use of mechanical suture for pharyngeal closure when buying it with manual suture by reducing the number of FFCs, operative time and days of hospitalization.

Fatores preditores de fístula salivar pós-laringectomia total / Predictors of salivary fistula after total laryngectomy

OBJETIVO: Avaliar a incidência de fístula faringocutânea após laringectomia total e tentar identificar os fatores preditores. MÉTODOS: No período de maio de 2005 a abril de 2010, 93 pacientes foram submetidos à laringectomia total. Foram avaliadas as complicações per e pós-operatórias e comparadas com as seguintes variáveis: sexo, estado nutricional, traqueostomia prévia, localização do tumor primário, tipo de operação realizada, estadiamento de acordo com o TNM, tratamento prévio com quimioterapia e/ou radioterapia, utilização de retalhos para reconstrução e margem cirúrgica. Todos os pacientes apresentavam a neoplasia em estádio avançado segundo o TNM. RESULTADOS: 14 (15,1%) pacientes evoluíram com fístula salivar no pós-operatório. O tempo médio de aparecimento da fístula salivar foi 3,5 dias, com desvio padrão de 13,7 dias. Comparando a fístula salivar com as variáveis TNM, tipo de operação e esvaziamento cervical, traqueostomia prévia, utilização de retalho miocutâneo, rádio e quimioterapia pré-operatória e margem cirúrgica, não foi observado diferença estatisticamente significativa (p>0,05). CONCLUSÃO: A incidência de fístula salivar foi 15,1% e não foi encontrado fator preditor para sua formação.

OBJECTIVE: To evaluate the incidence of pharyngocutaneous fistula after total laryngectomy and try to identify its predictors. METHODS: From May 2005 to April 2010, 93 patients underwent total laryngectomy. We evaluated complications during and after surgery and compared them with the following variables: gender, nutritional status, previous tracheotomy, tumor location, type of surgery, TNM staging, prior treatment with chemotherapy and/or radiotherapy, use of flaps for reconstruction and surgical margin. All patients presented with advanced neoplastic disease according to TNM. RESULTS: 14 (15.1%) patients developed postoperative salivary fistula. The mean time to onset of salivary fistula was 3.5 days, with a standard deviation of 13.7 days. Comparing salivary fistula with TNM variables, type of operation and neck dissection, prior tracheotomy, use of flap, preoperative radio and chemotherapy and surgical margin, there was no statistically significant difference (p> 0,05). CONCLUSION: The incidence of salivary fistula was 15.1% and no predictive factor for its formation was found.

Frequency of urethrocutaneous fistula following snodgrass hypospadias repair in children

To determine the frequency of urethrocutaneous fistula over a period of three months following snodgrass hypospadias repair for the treatment of distal penile hypospadias in children. This descriptive study was conducted in the pediatric surgery unit, Lady Reading Hospital, Peshawar over a period of eight months from June 2009 to February 2010. Patients with distal penilehypospadia without chordee between 2 and 14 years were included and patients were excluded who had previous repair for hypospadias. All those patients fulfilling the inclusion and exclusion criteria whose parents gave informed consent after explanation of the whole protocol were admitted through outpatient department for the said procedure and data was analyzed. A total of 52 patients were included in the study. All patients were in the range of 2 to 10 years and underwent Snodgrass Tubularized Incised Plate [TIP] urethroplasty for hypospadias repair. The overall rate of urethrocutaneous fistula was 9.6% [5 out of 52 patients]. Mean operative time noted in minutes was 57.52 minutes. No major morbidity or mortality was noted in this study. TIP urethroplasty is simple, single stage operation in the management of hypospadias and has good functional and low complication rate

Unproved tuberculous lesion of penis: A rare cause of saxophone penis treated by a therapeutic trial of anti-tubercular therapy.

Although Tuberculosis (TB) most commonly affects the lungs, any organ or tissue can be involved. In countries with comprehensive diagnostic and reporting systems, extrapulmonary tuberculosis (EPTB) accounts for 20-25% of reported cases. Globally, extrapulmonary cases (without concurrent pulmonary involvement) comprised 14% of notified cases (new and relapse) in 2007. The most common sites of extrapulmonary tuberculosis consist of lymphatic, genitourinary, bone and joint, and central nervous system involvement followed by peritoneal and other abdominal organ involvement. We report a case of a 25 year old male patient who came with multiple discharging sinuses and an urethrocutaneous fistula over the penis treated by a therapeutic trial of Anti-tubercular therapy (ATT).

Fístulas orocutâneas após cirurgia de câncer da cavidade oral: fatores de risco / Oral cancer surgery and oral cutaneous fistulas: risk factors

OBJETIVO: Quantificar as fístulas após cirurgia de câncer da cavidade oral e identificar fatores de risco. MÉTODOS: Estudo retrospectivo, interessando pacientes submetidos à cirurgia. Seguimento pós-operatório mínimo de dois anos. Variáveis estudadas: sexo, comorbidades, tabagismo, etilismo, risco anestésico e pulmonar, estadiamento clínico, linfadenectomia cervical, tratamento radioterápico, acidentes cirúrgicos, infecção ou deiscência de ferida operatória, seroma ou hematoma de sítio cirúrgico, infecção respiratória no pós-operatório, tipo de cirurgia e reconstrução realizadas. RESULTADOS: Estudados 159 pacientes. Ocorreu fístula orocutânea em 30,3 por cento (48 pacientes). Pacientes T3 tiveram fístula em 16 por cento dos casos, T4 em 40,3 por cento e naqueles estádio T1 ou T2, 26,6 por cento e 1,8 por cento respectivamente (p=0,0138). Os casos N+ evoluíram com fístula em 22.9 por cento (N2c com 42,8 por cento, p=0,0136), os com radioterapia pré-operatória em 63,6 por cento (p=0,0346). Aqueles com infecção de sítio cirúrgico em 47,3 por cento (p=0,0146) e aqueles com deiscência de ferida operatória em 53,7 por cento (p=0,0030). O índice de fístula foi de 60 por cento nos retalhos regionais mucocutâneos, de 39,2 por cento nos miocutâneos e de 12,5 por cento com retalho microcirúrgico (p=0,0286). CONCLUSÃO: O índice de fístulas foi de 30,3 por cento. Foram estatisticamente significativos para ocorrência de fístulas: estádio T, linfadenectomia cervical bilateral, radioterapia pré ou pós-operatória, infecção e deiscência de ferida operatória, e o uso de retalhos para reconstrução.

OBJECTIVE: To quantify the oral cutaneous fistulae after surgery and to identify possible risk factors. METHODS:A retrospective study, interesting patients that were submitted to surgery, with a two years minimum post-operative follow up. The considered variables were: sex, concomitant diseases, tabacco and alcohol use, the anesthesic and pulmonary risks, clinical stage, cervical linphadenectomy, pre or postoperative radiotherapy, accidents during the surgery, wound infection and or hematoma, pulmonary infection, surgery and reconstruction extension. RESULTS: In 159 patients, oral cutaneous fistulae occurred in 48 patients (30,3 percent): Patients stage T1 in 26,6 percent,T2 in 1,8 percent,T3 in 16 percent, and T4 in 40,3 percent (p=0,0138). The cases N+ developed fistulae in 22.9 percent, (N2c with 42,8 percent, (p=0,0136), those with preoperative radiotherapy in 63,6 percent (p=0,0346) Those with wound infection in 47,3 percent (p=0,0146), and those with wound deiscense in 53,7 percent (p=0,0030). The fistulae rate was of 60 percent in the regional mucocutaneous flaps reconstruction cases, 39,2 percent in the myocutaneous ones and 12,5 percent of microsurgery ones (p=0,0286). CONCLUSION: The general rate of oral cutaneous fistulae was 30,3 percent. The significant factors were: T stage, cervical linphadenectomy, pre or postoperative radiotherapy, wound infection and deiscense, and the use of flaps.

Postlaryngectomy pharyngocutaneus fistula in Imam Khomeini Hospital

Pharyngocutaneus fistula is the most common complication following total laryngectomy with an unknown multifactorial etiology. The present study was designed to determine the incidence and predisposing factors of pharyngocutaneus fistula. 76 patients who underwent total laryngectomy for laryngeal carcinoma were reviewed retrospectively. We evaluated factors potentially predisposing to fistula formation [age, sex, hypertension, congestive heart failure, pre- and post operative hemoglobin levels, tumor site, previous radiotherapy and chemotherapy, infection of surgical site, fever, concurrent neck dissection, smoking, drinking, peri-operative blood transfusion] using the chi-squared test, independent sample test and t-test. Pharyngocutaneus fistula was diagnosed in 10 patients [13.1%] within less than 4 weeks from surgery. Analysis showed that there were no statistically significant associations between fistula development and age, sex, hypertension, congestive heart failure, pre- and post operative hemoglobin levels, tumor site, previous radiotherapy and chemotherapy, concurrent neck dissection, smoking, drinking and peri operative blood transfusion. Infection of surgical margins and fever increased the risk of fistula development. The results show that infection of the surgical site and fever were associated with fistula formation. Given that fistula formation increases patients morbidity and hospital stay, prevention of surgical site infection and fever should be considered with an increased risk of pharyngocutaneus fistula formation

Factors predicting morbidity and mortality in intestinal fistulae.

INTRODUCTION: Intestinal fistulae are a daunting clinical problem. AIM: To evaluate the influence of various severity factors on morbidity and mortality in patients with intestinal fistulae. METHOD: In 29 patients with intestinal fistulae, eight severity factors, viz., age, associated bowel disease, anemia, hypoalbuminemia, high-output fistula, category IV fistula, excoriation of skin surrounding the stoma, and sepsis, were analyzed prospectively to assess their effect on healing of fistulae and mortality. Chi-squared test with Yates' correction was used. RESULTS: Age, presence of associated bowel disease, and hemoglobin levels had no significant effect on healing or mortality. Hypoalbuminemia, category IV fistulae, presence of local skin excoriation, and sepsis significantly delayed healing (p < 0.05). High-output fistula, category IV fistula, local skin excoriation, and sepsis were significantly associated with high mortality (p < 0.05). CONCLUSION: Identification of these prognostic factors in intestinal fistulae may guide the need for more intensive care or intervention.